We investigate if the mechanisms of degeneration in MND are shared with other degenerative conditions, in order to develop treatments that prevent or even reverse cognitive decline.

Professor Tara Spires-Jones

Professor of Neurodegeneration
Centre for Discovery Brain Sciences

Email: tara.spires-jones@ed.ac.uk

My group investigates the causes of cognitive decline in neurodegenerative diseases and ageing.   We hypothesize that the degeneration of synapses, the connections between neuronal cells in the brain, causes cognitive impairment and that targeting the causes of synaptic degeneration will allow recovery of cognitive function.  The lab uses high-resolution imaging of transgenic models and human brain tissue to probe the mechanisms of disease progression with the aim of finding pathways to target with drugs.

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