Two Edinburgh researchers have recently become Principal Investigators of the Euan MacDonald Centre. We would like to welcome them both and wish them well in their research.
Dr Lyndsay Murray completed her doctoral studies at the University of Edinburgh and graduated in 2010. Since then, she has been a postdoctoral fellow at the Ottawa Hospital Research Institute in Ontario, Canada. She is now excited to return to Edinburgh as a Lecturer in Anatomy and start her own research group.
Lyndsay’s research is centered on understanding the cellular and molecular mechanisms that lead to motor neuron degeneration in the childhood motor neuron disease, spinal muscular atrophy. Specifically, she is interested in investigating both the transcriptional changes which initiate motor neuron pathology, and the compensatory mechanisms which protect specific motor neuron pools.
Dr Xavier Donadeu is a Group Leader at the Roslin Institute and Senior Lecturer at the Royal (Dick) School of Veterinary Studies. He qualified as a vet in Spain and undertook postdoctoral research in the USA before joining the University of Edinburgh in 2005.
One of Xavier’s lines of research focuses on using equine induced pluripotent stem cells towards the derivation of clinically relevant tissues. He recently published his research describing the generation of stem cell-derived equine motor neurons; this work may pave the way for cell therapies that target conditions similar to motor neurone disease.