Centre researchers shed new light on the effectiveness of a neuroprotective gene for protecting the aging brain
Dec 2010
A new study from Ann Wright, Tom Wishart, Cali Ingham and Tom Gillingwater has shown that the neuroprotective WldS gene can protect sites of nerve communication in the aging brain. The study, just published in PLoS One, shows that the WldS gene can protect synapses in the aging brain from degeneration. This finding is important because it suggests that targeting those pathways used by the WldS gene may provide novel therapeutic approaches for preventing and delaying neurodegeneration in the aging nervous system.
Full paper details: Wright AK, Wishart TM, Ingham CA, Gillingwater TH. Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose. PLoS One. 2010 5;e15108
The full paper can be downloaded from: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0015108
