Motor Neurone Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s Disease, is a debilitating neurological disease that results in the degeneration and death of the large motor neurones in the brain and spinal cord. This leads to muscle weakness resulting in loss of mobility and difficulties with speech, swallowing and breathing.
Some treatments can ameliorate symptoms, but there are currently no treatments that can halt or reverse the progression of the disease.
For over 95% of cases of MND, identifying the causes has defied decades of research. Understanding why and how the neurones die is a fundamental precursor to the development of new therapies. MND may share the cardinal mechanisms of neurodegeneration with other neurological diseases such as multiple sclerosis, Alzheimer’s disease, Parkinson’s disease and Huntington’s disease. For this reason, the interdisciplinary and collaborative nature of the research at the Euan MacDonald Centre is of vital importance.
For information on living with MND
If you are living with MND in the UK, know someone who has been diagnosed with the disease, or care for someone living with it, the following websites will provide you with further information: